‘Dark DNA’ Is the Latest Mystery in the World of Genetics… But What Is It?

‘Dark DNA’ Is the Latest Mystery in the World of Genetics… But What Is It?


Dark matter is one of the biggest mysteries
of astronomy today. There’s tons of evidence that it’s there,
but try as we might we haven’t been able to find it. In biology there’s a similar problem: dark
DNA. When scientists were exploring the sequenced
genomes of certain birds and rodents they noticed something odd. A sequenced genome means everything is laid
bare, and yet certain DNA sequences were missing, which was weird because these DNA sequences
were very important. They controlled the production of leptin in
the birds or the secretion of insulin in the rodents, genes that the scientists knew had
to be there, otherwise they’d have some mighty obese birds and dead rodents on their
hands. What’s more, the scientists studying the
rodents found the products of the missing DNA sequences in their cells, so they deduced
that the genes weren’t missing, but were somehow hidden. They dubbed these elusive sequences “dark
DNA.” Sounds spooky, but the reality is this dark
DNA may be more of a blind spot in our DNA sequencing technology than anything else. A closer look at the rodent’s genome found
a heavily mutated section with abnormally high amounts of guanine and cytosine, two
of DNA’s four base molecules, called G and C for short. It turns out GC rich sequences are difficult
to detect, so the researchers missed this mutated pocket of DNA at first. This dark DNA raises questions about how quickly
mutations occur, and what genes we may have missed when we sequenced other genomes like
our own Which is crazy to think that there could be
more DNA in us than we realized, especially when you consider that we only know what about
1 to 2% of the stuff we have found does. Those sections code proteins that have some
function. The other 98%-ish doesn’t make anything
and so we don’t know why it’s there. This vast amount of genetic code has also
been referred to as DNA’s “dark matter.” Apparently biologists love the dark matter
analogy, only the kind we’re talking about now is the opposite of the first example. Instead of knowing what a gene does but not
finding it, we’ve found a lot of genes but have no idea what they do. Slowly though we’re chipping away at that
riddle too. It appears that a lot of this non-coding DNA
is still helpful for regulating gene expression, making sure the right cells have the right
hardware, like hemoglobin in blood cell precursors and ion channels in neurons. Some of these sequences are almost identical
across different species like humans, mice and chickens. Considering we’ve been evolving separately
for up to 200 million years, researchers concluded that these sequences must somehow be vital
to our survival. When researchers deleted four of these genes
in mice, they found abnormalities in the mice’s brains, and wondered if mutations in these
overlooked non-coding sections of DNA could be responsible for brain diseases like alzheimer’s. So there is a lot of DNA to parse through
and there could be even more we just haven’t found because of limitations in our sequencing
techniques. Our genome is still a pretty dark and mysterious
place, and more research is needed. One quick thing. Seeker needs your help! Please vote for us to win a People’s Choice
Webby! You’re the people you get to choose, you like
us, it works! We made an awesome virtual reality doc that
lets you experience what it’s like to climb Mt. Everest, and it is a finalist in the VR
category for the Webby Awards. The Seeker Everest VR Expedition mixes elements
of interactive documentary with the immersion of virtual reality to bring you into a first-person
narrative from one of the most inaccessible places on Earth. We are super excited about receiving this
honor, and we would be even more excited if we won, so please, get out and give us a vote,
and if we win, we will give you, our viewers a special surprise. Voting is open until Thursday, April 19th. Click the link in the description to vote. What are you waiting for? It’s not like climbing Mount Everest, just
click that and go vote! Awesome! And then check out VR Mt. Everest, it’s super
cool. Researchers believe that the rodents’ hot
spots of DNA mutation could be evidence of an undiscovered and rapid mechanism of evolution. There are known cases of rapid evolution. To learn more about ways species can shift
in years instead of millenia, check out Trace’s video here. That’s it for now, I’ll see you next time
on Seeker.

Posts created 35593

100 thoughts on “‘Dark DNA’ Is the Latest Mystery in the World of Genetics… But What Is It?

  1. "so there's this thing. we don't know what it is. wow, isn't that cool! if only we had more money…" end of video

  2. It's probably a hacked code sequence that is capable of storing information both forwards and backwards, like a strategically written algorithm. Thus, it's stores extra information in what we would call a compressed manner.

  3. Is an informal for genetic material or microorganism that are unclassified or understood.Includes noncoding DNA and non-coding RNA. 🐶

  4. "Mount Everest"? Indian Himalayas which had been the home for thousands of ultra-endurance rishis who have went to the peaks since millenia is named after a white man? Really? White people and their "everything is mine" white privilege stupidity never ceases to amaze me.

  5. Were so smart we just found blood vessels and soft collagen in a T-Rex bone 75 million years old because no one thought it would ever last a 100,000

  6. Yeah, apparently EVERYONE really loves the 'dark' analogy. I can't wait until psychologists start calling the subconscious part of our mind/brain the 'dark consciousness.' That'll be just great. Ugh. Anyway, as I've been saying since people started bandying about the term, 'junk DNA' (oh, look – there's yet ANOTHER term I'm excruciatingly sick of…), if you want to build an organism inside another organism, the instructions might just include periods of waiting. It seems that this could possibly explain some of the 'junk DNA,' though certainly not all of it. As to 'dark DNA,' it makes me think of hidden coding in a computer program – a crude, but maybe effective, analogy. It's possible that this idea could be used by life in an attempt to protect certain crucial areas of DNA. Not a perfect system, by any means, but hey, it's a thought, Rikki Tikki.

  7. It just means that we just don't fully fucking understand mammal biology, just as we don't fully fucking understand the intricacies of cosmology.

  8. This is the most interesting video I have seen in awhile , sadly the topic is less then 3 minutes with advertising for future videos almost taking up the last sixty seconds.

  9. You clearly know nothing at all about this Biotech field and just for the sake of MAKING VIDEOS , u made this ….
    absolutely crap
    the part of the dna that doesnt code for proteins is called the intron part not the Dark DNA …
    shame.
    and its there to lower the chances of mutation ,,,, seriously?
    DARK DNA
    Gimme a break XD

  10. Can there be a very important dark dna effect that that perhaps requires a presence of , for ex. High blood sugar to emancipate great physical strength at time of need as I have experienced in an almost fatal auto accident many years ago. I have an allergic response to insulin now tho I am told I am a type 2 diabetic.. can some people have a quick mutation as you explain. Please keep up this fascinating research. Agnes Temesvari

  11. Could 'wave packets' of light for example be photon particles that are in orbit with undetectable dark matter particles pulling them into polarizable axial or helical apparent waves as they travel where the speed of their orbit is the wavelength and the diameter is the amplitude which would explain the double slit, uncertainty, etc?

  12. A different perspective. The Scientific powers that be labeled unused DNA as "junk" to dissuade the public sector from looking seriously into it's function. I suspect "they" have hit a roadblock and now are re-branding it as "Dark DNA" to spark interest from the public sector hoping to gain new insights that have so far eluded them. https://www.theguardian.com/science/occams-corner/2014/aug/15/who-governs-science

  13. They should use AI and feed it all the DNA data and it's correspondent species and information, that way it can map out WAYYY more without needing to manually research every single combination of genes.

  14. Let me see DNA 10 years ago..1% we know of DNA now 5% we know it works for solving cold cases better then fingerprints..dark DNA is a true meaning of..shit we can't get past the 5% mark because we keep looking for really hard answers….its like nerves 1/16 of a bad nerve takes about 6 months to cure..but as we keep using that damaged nerve it will now take upto a year to cure…if you understand that then you will understand why we can't advance in DNA…lucky we got this far..the secret is you can't view a live event because it knows your watching and it will change..like the double split theory…peace and may your god be with you…

  15. complete thesis…. But is incredible to think about, and could be the reason behind MANY unexplained and great questions of the universe. 👍

  16. milyen kár hogy 12 év alatt feke média gyors fejlodést csinált :))))))))) tehát mit is értek el?:)))))) megmutaták megkora seggfejek :))))))))) nagyhatalmak :)))

  17. LIKE THE BRAINS POTENTIAL,DNA-RNA HAS A POTENTIALITY THAT IS STIMULATED BY ENERGIES OF HIGHER CONSCIOUSNESS.THE KUNDALINI PARADIGM,S MODEL HAS A SINGLE HELIX:THE PINGALA-ANTIMATTER & IDA-MATTER,DYNAMIC.WHEN THIS HELIX BEGINS TO VIBRATE AT A HIGHER FREQUENCY THE BODY'S DNA OPERATES LIKE MANY MICRO ANTENNAS.WHEN THE WHOLE GENETIC CIRCUITRY IS IN ENTRAINMENT THE EVOLUTIONARY POTENTIAL OF OUR DNA & BRAIN IS REALIZED.SEE WEBSITE HINDU SAGE:GOPI KRISHNA.

  18. Every and that is to say EVERY ""study"" ends with ….more study is needed a.k.a. we want more money and as long as the money keeps coming we'll continue to pretend to be making some kind of progress by calling stuff "dark" this and "complex" that and make you think that any and all of this crap will forever be way beyond your ability to understand any of it so stop trying because our ability to over complicate and bewilder you is infinite and so we professionals will continue to mystify you because if you were to find out that at least 80% of all we do is pure bullshit you would hang us with sharp barbwire and even worse……….demand that all that wasted money be returned!!!

  19. could you guys make a video of how exactly do scientists gene edit any embryo? I'm asking because of the recent news of a mad scientist that gene edit twin babies in china.

  20. Dark matter is antimatter it's just matter with oppasite charges and when scientists make antimatter it makes matter disappeare the more they make the more are reality disappears

  21. Bullshit lies and ignorant….they are data mining people for your ideas on the internet….Researchgate.com project breakthrough and SETI all looking for your shit….and lying

  22. Can you please at least try to understand the subject you warble so willingly about?
    The amount of correct information in this video is essentially nil!
    Down voted with extreme contempt! :/

  23. Is it hard to believe that maybe, just maybe, the millions of nucleotides between all the important genes in our DNA is just filler? Sure, occasionally (more like very likely) you'll have parts in that filler that actually code into a gene and can yield a protein.. But it's filler protein. A product of random association under chaos.. The actual important genes, the ones that code everything we live with, are spaced out and spliced together into such a manner where they never get left behind……… I do think that we can program the filler DNA space with secret genes that do special functions that we want it to do. Sounds super cool.

  24. having been embarrassed to find that 'junk DNA' is not really thing the geneticists are changing their terms, thinking that we will not notice…just like 'global cooling' (1970s), 'global warming (so 80s-90s), and now it is 'climate change', like anyone has ever denied that climate changes…duh…

  25. OUR DNA IS NOT DARK OR JUNK!!!! OUR DNA IS MAGNETIC AND MULTI DIMENSIONAL… OUR DNA IS QUANTUM AND MOST OF IT IS OUR AKASHIC RECORDS FROM OUR SOULS EVERY INCARNATION CYCLE. ONCE WE STOP POISONING OUR BODIES AND SET OUR MINDS INTENT ON OBTAINING A HIGHER VIBRATIONAL ENERGY FREQUENCY AND RAISE OUR DNA LEVEL THEN WE WILL KNOW THIS FACT AND SOON AFTER REALIZE THAT CONCIOUSNESS IS PHYSICS AND MAGNETISM IS MUCH BIGGER THAN WE HAVE YET TO ACKNOWLEDGE OR UNDERSTAND… MASS AND GRAVITY ARE MALLEABLE AND CAN BE MANIPULATED AND ALTERED USING VIBRATIONS AND FREQUENCIES ECT. ECT….. DILLY DILLY ♒⚕🕉☯️♾💙💚🧡🎨🍍🎶

  26. There isn't 'tons os evidence' for dark matter. Just tons of evidence that current cosmological theories are flawed. Dark matter is literally a fudge factor.

  27. im not sure if i voted correctly, but i keep clicking the link but nothing happens, searching on that site 'seeker' isn't finding it

  28. I would be impressed if we could change a cold blooded animal to a warm blooded animal , normal mammals given the sight of a bird or a cat , the search between these dimensions could possibly be given to a blind person as the development gets better or even throgh A.i and camera systems, what can a Quantum computer say about connecting to the energy in a blood stream only in the eyes

  29. DNA is great but we study dead cut up DNA it's not the same not to mention not all DNA is in one place.

  30. I think that a great deal of our genes are only active during formation. After we are adults only a tiny portion of our DNA remains active. And most of our DNA is in fact historical genes related to our ancestry that are no longer active. This means that our DNA could actually be much smaller but cells do not choose what can be discarded, it's more likely to keep cumulating new genes.

  31. I did my family tree on my heritage page.I wonder how Unique people we have in the family.I just want to make some project,how the faces changed after years.

  32. I just think it's really fun how some people support GMO and yet every few years the genetic researches come out with a whole new epiphany about how what little they thought they knew about DNA is in fact even less

  33. I like your channel becoz science is something wow u can ask about the dark which is surrounded in every way and this energy creator create many other things in itself

  34. So vaccines residue and byproducts can merge into this dark dna and go "dark" untill it triggers and merges with other cells…causing diseases?

  35. Advance humans altered our DNA for the purpose of constructing the new world Order. Essentially making us watered down; weaker, less intelligent, make us age faster, and die faster and etc. In my opinion I believe that we’ve been lied to about our origins, religions and our history.

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